Meguiars M66 User Manual download pdf (Page 9)

M66, Quick Detailer (21-141A): M6601

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Page: 9 of 17

Carcinogenicity

Name Route Species Value

Naphtha (petroleum), hydrotreated heavy Dermal Mouse Some positive data exist, but the data are not

sufficient for classification

Naphtha (petroleum), hydrotreated heavy Inhalation Human

and

animal

Some positive data exist, but the data are not

sufficient for classification

Distillates (petroleum), hydrotreated light Dermal Mouse Some positive data exist, but the data are not

sufficient for classification

Ceramic materials and wares, chemicals Inhalation Multiple

animal

species

Some positive data exist, but the data are not

sufficient for classification

Stoddard solvent Dermal Mouse Some positive data exist, but the data are not

sufficient for classification

Stoddard solvent Inhalation Human

and

animal

Some positive data exist, but the data are not

sufficient for classification

White mineral oil Dermal Mouse Not carcinogenic

White mineral oil Inhalation Multiple

animal

species

Not carcinogenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-

2H-isothiazol-3-one

Dermal Mouse Not carcinogenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-

2H-isothiazol-3-one

Ingestion Rat Not carcinogenic

Reproductive Toxicity

Reproductive and/or Developmental Effects

Name Route Value Species Test result Exposure

Duration

Naphtha (petroleum), hydrotreated heavy Inhalation Not toxic to development Rat NOAEL 2.4

mg/l

during

organogenesis

Stoddard solvent Inhalation Not toxic to development Rat NOAEL 2.4

mg/l

during

organogenesis

White mineral oil Ingestion Not toxic to female reproduction Rat NOAEL

4,350

mg/kg/day

13 weeks

White mineral oil Ingestion Not toxic to male reproduction Rat NOAEL

4,350

mg/kg/day

13 weeks

White mineral oil Ingestion Not toxic to development Rat NOAEL

4,350

mg/kg/day

during

gestation

Mixture of 5-chloro-2-methyl-2H-

isothiazol-3-one and 2-methyl-2H-

isothiazol-3-one

Ingestion Not toxic to female reproduction Rat NOAEL 10

mg/kg/day

2 generation

Mixture of 5-chloro-2-methyl-2H-

isothiazol-3-one and 2-methyl-2H-

isothiazol-3-one

Ingestion Not toxic to male reproduction Rat NOAEL 10

mg/kg/day

2 generation

Mixture of 5-chloro-2-methyl-2H-

isothiazol-3-one and 2-methyl-2H-

isothiazol-3-one

Ingestion Not toxic to development Rat NOAEL 15

mg/kg/day

during

organogenesis

Target Organ(s)

Specific Target Organ Toxicity - single exposure

Name Route Target Organ(s) Value Species Test result Exposure

Duration

Naphtha (petroleum),

hydrotreated heavy

Inhalation central nervous

system depression

May cause drowsiness or

dizziness

Human

and

animal

NOAEL Not

available

Naphtha (petroleum),

hydrotreated heavy

Inhalation respiratory irritation Some positive data exist, but the

data are not sufficient for

classification

NOAEL Not

available

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