Meguiars A33 User Manual download pdf (Page 7)

A33, Quik Detailer (19-187B): A3316, A3332

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Page: 7 of 12

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

Rabbit Corrosive

Serious Eye Damage/Irritation

Name Species Value

1-propoxypropan-2-ol Rabbit Severe irritant

Propane-1,2-diol Rabbit No significant irritation

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

Rabbit Corrosive

Skin Sensitisation

Name Species Value

Propane-1,2-diol Human Some positive data exist, but the data are not

sufficient for classification

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

Human

and

animal

Sensitising

Photosensitisation

Name Species Value

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

Human

and

animal

Not sensitizing

Respiratory Sensitisation

Name Species Value

Germ Cell Mutagenicity

Name Route Value

1-propoxypropan-2-ol In Vitro Not mutagenic

Propane-1,2-diol In Vitro Not mutagenic

Propane-1,2-diol In vivo Not mutagenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

In vivo Not mutagenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-

one

In Vitro Some positive data exist, but the data are not

sufficient for classification

Carcinogenicity

Name Route Species Value

Propane-1,2-diol Dermal Mouse Not carcinogenic

Propane-1,2-diol Ingestion Multiple

animal

species

Not carcinogenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-

2H-isothiazol-3-one

Dermal Mouse Not carcinogenic

Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-

2H-isothiazol-3-one

Ingestion Rat Not carcinogenic

Reproductive Toxicity

Reproductive and/or Developmental Effects

Name Route Value Species Test result Exposure

Duration

1-propoxypropan-2-ol Inhalation Some positive developmental data exist,

but the data are not sufficient for

classification

Rat NOAEL 3.6

mg/l

during

organogenesis

Propane-1,2-diol Ingestion Not toxic to female reproduction Mouse NOAEL

10,100

mg/kg/day

2 generation

Propane-1,2-diol Ingestion Not toxic to male reproduction Mouse NOAEL

10,100

mg/kg/day

2 generation

Propane-1,2-diol Ingestion Not toxic to development Multiple NOAEL during

1 2 3 4 5 6 7 8 9 10 11 12

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